4beta-hydroxycholesterol in Cirrhosis

N/ASuspendedNCT04199910

University of Oulu120 enrolled

Overview

The aim is to evaluate the levels of oxysterols and especially 4beta-hydroxycholesterol in patients with liver cirrhosis. Three cirrhosis cohorts are recruited: patients treated with spironolactone, patients treated with rifaximin, patients without spironolactone or rifaximin. Also three other control cohorts are recruited: patients with pneumonia, patients with Crohn's disease, patients with ulcerative colitis. The effect of the cirrhosis and its medications spironolactone and rifaximin are compared to control groups.

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

Cirrhosis, Liver

Interventions

There is no intervention, only research blood samples are collectedOTHER

Research blood samples collected

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with cirrhosis, pneumonia, Crohn's disease or colitis ulcerosa * Treated in the ward 42 of the Oulu University Hospital Exclusion Criteria: * None

Locations (1)

Oulu University Hospital

Oulu, Finland

Outcomes

Primary Outcomes

Blood 4beta-hydroxycholesterol concentration

Time frame: At the time point of the blood collection - cross-sectional. One day.

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.