Chemoembolization for Lung Tumors

Inclusion Criteria: * Lung, endobronchial, pleural, or mediastinal metastases that are not responding to systemic chemotherapy, and that are not amenable to ablation, resection, or SBRT. * At least 18 years old. * ECOG performance status 0 or 1 Exclusion Criteria: * Primary lung cancer * \>50% of a lung is replaced with tumor * Oxygen saturation \<92% on room air * FEV1 \<60% * Pulmonary hypertension (diagnosed or suspected on echocardiography, CT, MRI, or direct pressure measurement) * Recent pulmonary embolism (within 3 months) * Pulmonary arteriovenous malformation * Active lung infection (pneumonia, empyema, or lung abscess requiring therapy within 1 month) * Symptomatic heart failure (dyspnea, volume overload) * Left bundle branch block (contraindication to pulmonary angiography) * Renal failure (eGFR \<30 mL/min/1.73m\^2) * Pregnancy * Breastfeeding * Altered mental status that would interfere with consent or follow-up * Platelets \< 100,000 (after transfusion, if needed) * INR\>2 (after transfusion, if needed) * Hemoglobin \<7 (after transfusion, if needed) * Hyperthyroidism (contraindication to lipiodol) * Planned radioactive iodine imaging or therapy (contraindication to lipiodol) * Allergy to lipiodol or mitomycin * Allergy to iodinated contrast that can not be treated with steroid / diphenhydramine premedication * Any condition that, in the opinion of the investigator, would interfere with evaluation of the investigational product or interpretation of subject safety or study results