The aim of the study was to investigate the possible relationship about blood gas and bleeding disorders in healthy volunteers of blasters and no blasters groups of the Italian National Mountain and Cave Rescue who handled nitrogen compounds and nitroglycerine and then they were exposed to combustion products from an accidental uncontrolled detonation of micro-charges during a cave unblocking procedure.
This was a field report of clinical data collected during an accidental uncontrolled detonation of micro-charges, while the cave unblocking procedure was performed by volunteers of blaster group and non blasters group of the Italian National Mountain and Cave Rescue, in a cave in Trieste (Italy; altitude entrance: 348 meters above sea level; total length: 413,5 meters; total depth of 307 meters). Before going into the cave (Time 0), the following clinical data were collected: age, sex, body mass index; smoke (yes/no), heart rate, arterial blood pressure (mean arterial pressure), oxygen saturation measured with pulse oxymetry, epitympanic temperature, blood gases analyses and the haemostasis measures. After the accidental uncontrolled detonation of micro-charges, (Time 1) heart rate, arterial blood pressure, oxygen saturation measured with pulse oxymetry, epitympanic temperature, blood gases analyses and the haemostasis measures were recorded in each volunteers.
Study Type
OBSERVATIONAL
Enrollment
94
Under aseptic conditions, a puncture of radial artery was performed: three mL of the arterial blood sample were used for the haemostasis measure, while one mL was tested for the blood gases analysis.
Barbara Pizzi
Avezzano, Italy
Change from baseline arterial blood gases analysis at 2 hours
Under aseptic conditions, a puncture of radial artery was performed: one mL was tested for the blood gases analysis, by using i-STAT analyser.
Time frame: 10 minutes before going in to the cave and two hours after the volunteers come out from the cave
Change from baseline haemostasis analysis at 2 hours
Under aseptic conditions, a venipuncture was performed: three mL of blood sample were used for the haemostasis measure, by using Rotational Thromboelastometry
Time frame: 10 minutes before going in to the cave and two hours after the volunteers come out from the cave
Change from Baseline heart rate at 2 hours
Haert rate was recorded by using a multiparametric monitor
Time frame: 10 minutes before going in to the cave and two hours after the volunteers come out from the cave
Change from baseline arterial blood pressure at 2 hours
Arterial blood pressure was recorded by using a multiparametric monitor
Time frame: 10 minutes before going in to the cave and two hours after the volunteers come out from the cave
Change from baseline pulse oxymetry at 2 hours
Pulse oxymetry was recorded by using a multiparametric monitor
Time frame: 10 minutes before going in to the cave and two hours after the volunteers come out from the cave
Change from baseline epitympanic temperature at 2 hours
Epitympanic temperature was measured by using epitympanic probe
Time frame: 10 minutes before going in to the cave and two hours after the volunteers come out from the cave
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