The primary purpose of this study is to investigate the effectiveness reflected by the retention rate of perampanel as the only add-on treatment in adult participants with primary generalized tonic-clonic (PGTC) or secondarily generalized tonic-clonic (SGTC) seizures based on focal or idiopathic generalized epilepsy in a non-interventional (observational) setting.
Study Type
OBSERVATIONAL
Enrollment
187
Perampanel tablets.
Perampanel oral suspension.
Eisai Trial Site #51
Percentage of Participants Remaining on Perampanel at Month 12 (Retention Rate)
The retention rate is defined as the percentage of participants remaining on perampanel treatment at 12 months after the initiation of treatment.
Time frame: Month 12
Percentage of Participants Remaining on Perampanel at Month 6 (Retention Rate)
The retention rate is defined as the percentage of participants remaining on perampanel treatment at 6 months after the initiation of treatment.
Time frame: Month 6
Percentage of Participants Who Achieved Seizure Freedom for All Generalized Tonic-clonic (GTC) Seizures at Month 12
Time frame: Month 12
Number of Participants With Any Treatment-emergent Adverse Event (TEAE), Treatment-emergent Serious Adverse Events (SAE), and Adverse Events (AEs) by Severity
AEs will be graded on a 3-point scale that is mild (discomfort noticed, but no disruption of normal daily activity), moderate (discomfort sufficient to reduce or affect normal daily activity), and severe (incapacitating, with inability to work or to perform normal daily activity).
Time frame: Up to Month 12
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Aalen, Germany
Eisai Trial Site #12
Berlin, Germany
Eisai Trial Site #43
Berlin, Germany
Eisai Trial Site #15
Bernau, Germany
Eisai Trial Site #8
Bielefeld, Germany
Eisai Trial Site #53
Bochum, Germany
Eisai Trial Site #38
Bonn, Germany
Eisai Trial Site #9
Bonn, Germany
Eisai Trial Site #25
Damp, Germany
Eisai Trial Site #48
Dortmund, Germany
...and 24 more locations