Long-term, multicenter, multinational, observational, registry of patients with gMG that is designed to collect data on clinical outcomes and safety in patients prescribed Alexion C5 inhibitor therapies (C5IT) such as eculizumab (Soliris®) and ravulizumab (Ultomiris®).
At the time of enrollment in the Registry, participant records will be queried for retrospective information about the participants' medical history and gMG disease treatment history. Following enrollment, prospective data collection will be performed using data obtained as part of the routine clinical care and through patient-reported outcome methods in use. Data will be collected using an electronic data capture system. The duration of data collection for the Registry will be up to 5 years from the day of enrollment.
Study Type
OBSERVATIONAL
Enrollment
500
Change in Myasthenia Gravis Activities of Daily Living (MG-ADL) Score
The MG-ADL is an eight-item patient-reported outcome measure assessing MG symptoms and functional activities related to activities of daily living.48 Each of the items is scored from 0 (normal) to 3 (most severe), providing a total MG-ADL score ranging from 0 to 24, where higher scores indicate greater severity of symptoms.
Time frame: Approximately 5 years from enrollment
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Clinical Trial Site
Birmingham, Alabama, United States
RECRUITINGClinical Trial Site
Scottsdale, Arizona, United States
RECRUITINGClinical Trial Site
Fresno, California, United States
RECRUITINGClinical Trial Site
Orange, California, United States
RECRUITINGClinical Trial Site
Rancho Mirage, California, United States
RECRUITINGClinical Trial Site
Sylmar, California, United States
RECRUITINGClinical Trial Site
Colorado Springs, Colorado, United States
RECRUITINGClinical Trial Site
Fort Collins, Colorado, United States
RECRUITINGClinical Trial Site
New Haven, Connecticut, United States
RECRUITINGClinical Trial Site
Washington D.C., District of Columbia, United States
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