This observational study reports meropenem and piperacillin plasma concentrations in patients treated with either antibiotic and simultaneous continuous renal replacement therapy (CRRT).
Study Type
OBSERVATIONAL
Enrollment
135
Plasma concentration measurements
Karolinska University Hospital Solna
Stockholm, Sweden
Plasma antibiotic concentrations at mid and end of dosing interval
We vill report the measured plasma antibiotic concentrations at the mid and end of the dosing interval.
Time frame: 1 week
Plasma antibiotic concentrations at mid and end of dosing interval
The percentage of patients having a concentration above the highest MIC (minimal inhibitory concentration) breakpoint for pathogens considered susceptible for the antibiotic.
Time frame: 1 week
Relationships between plasma antibiotic concentrations and CRRT dose.
We will report the correlation between measured plasma concentrations of either antibiotic and the intensity of the CRRT treatment.
Time frame: 1 week
Influence of residual diuresis on the measured plasma antibiotic concentrations.
We will report the correlation between measured plasma concentrations of either antibiotic and residual diuresis.
Time frame: 1 week
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