Postoperative ileus is a common complication after major abdominal surgery. A positive effect of coffee to bowel movement has been described after colorectal and gynecologic interventions. The objective of this randomised controlled trial is to investigate whether the implementation of a fast track protocol with early coffee consumption accelerates the recovery of bowel function after pancreaticoduodenectomy.
Postoperative ileus (POI) is a common disorder after major abdominal surgery, affecting up to 40% of patients undergoing laparotomy. POI is described as the time between surgery and the first passage of flatus and/or stool and tolerance of oral diet. It could be recognised as postoperative complication when is defined as two or more of nausea/vomiting, inability to tolerate oral diet over 24 h, absence of flatus over 24 h, abdominal distention and radiologic confirmation on or after day 4 postoperatively without prior resolution. Multimodal approaches have been described to treat POI; among them, the early consumption of coffee showed a substantial benefit after colorectal and gynecologic surgery. The objective of this randomised trial is to investigate whether early coffee consumption can accelerate the recovery of bowel function after open pancreaticoduodenectomy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
204
One 30 mL espresso cup administered twice a day (08.00 a.m. and 02.00 p.m.).
One 30 mL espresso cup administered twice a day (08.00 a.m. and 02.00 p.m.).
One 30 mL espresso cup administered twice a day (08.00 a.m. and 02.00 p.m.).
AOUI Verona
Verona, Italy
First Bowel Movement
Time to first bowel movement (expressed by hours from the time of surgical procedure ending).
Time frame: 96 hours.
First Flatus
Time to first flatus (expressed by hours from the time of surgical procedure ending).
Time frame: 96 hours
Tolerance to solid food
Time to tolerance to solid food (expressed by hours from the time of surgical procedure ending). Tolerance was defined as the ability to eat at least half of the solid food served by hospital staff.
Time frame: 96 hours
Length of stay
Length of stay expressed by days from intervention to discharge.
Time frame: 90 days
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