FTO Gene Variants and Diet in Obesity

N/ACompletedNCT04205318

Hacettepe University400 enrolled

Overview

Studies have shown that the effect of fat mass and obesity-associated (FTO) gene on obesity is modulated by lifestyle factors. Hence, we aimed to determine whether two single nucleotide polymorphisms (SNPs) in the FTO gene are associated with obesity and to assess whether these associations were modified by lifestyle factors. The study included 200 obese and 200 non-obese individuals from Turkey. Our study suggests that the effect of the SNPs on obesity traits is likely to be influenced by lifestyle factors in this Turkish population.

Study Type

OBSERVATIONAL

Enrollment

400

Conditions

Obesity Diet Habit Genetic Predisposition

Eligibility

Sex: ALLMin age: 24 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. attending routine outpatient visits, 2. aged 24 to 50 years, 3. having a BMI ≥ 18.50 kg/m2

Locations (1)

Zehra Buyuktuncer

Ankara, Turkey (Türkiye)

Outcomes

Primary Outcomes

Genetic analysis of two SNPs at FTO gene

FTO SNPs rs9939609 and rs10163409

Time frame: up to 36 weeks

Anthropometric measurements

Body mass index, waist circumference, hip circumference, body composition

Time frame: up to 36 weeks

Biochemical measurements

lipid profile, glucose, insulin, adiponectin

Time frame: up to 36 weeks

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.