It is unclear whether individual treatment of scabies is similarly effective compared to household treatment. This study therefore compares these two treatment strategies with topical benzyl benzoate for treating scabies in Lambaréné and surroundings in Gabon. Subjects presenting with uncomplicated scabies are randomized into either the Individual Treatment group, where only the affected subjects receive treatment, or the Household Treatment group, where all family members are treated in parallel to the affected subjects regardless of signs and symptoms. The primary endpoint is clinical cure after 28 days; the secondary endpoint is the proportion of affected household members per household after 28 days.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
104
Applied to skin for the treatment of scabies
Centre de Recherches Médicales de Lambaréné
Lambaréné, Gabon
Number of Participants With Clinical Cure
clinical improvement in skin lesions with no new lesions occurring since treatment application as assessed by skin examination
Time frame: after 28 days from baseline
Proportion of Affected Household Members Per Household
proportion of scabies cases per household after 4 weeks
Time frame: after 28 days from baseline
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