Study of Drug Exposure in Systemic Circulation of Primatene Mist by Oral Inhalation, Versus Epinephrine Injection by Intramuscular Injection and ProAir by Oral Inhalation in Healthy Individuals

Inclusion Criteria: * Agree to participate; understand and sign informed consent; * Male and female adults, aged 18 to 50 years, inclusive at Screening; * Generally healthy and medically stable, with no clinically significant abnormalities based on physical examination and laboratory tests as determined by the Investigators; * Have good venous access; * Have normal resting blood pressure and normal heart rate (HR) without history of syncope; a subject with out of range blood pressure may be enrolled in the study at the discretion of the Principal Investigator; * Have a body mass index (BMI) of 18.0 - 30.0 kg/m\^2; * Female candidates must be \>1 year post-menopausal or practicing a clinically acceptable form of birth control and confirmed by negative urine or serum pregnancy test at Screening; * Negative HIV-Ab, HBs-Ag and HCV-Ab; * Negative alcohol test (urine or breathalyzer); * Negative drug screening results; * Currently non-smoker; have not used any tobacco products for at least three (3) months prior to Screening; and * Demonstrate proficiency in the use of MDI and a consistent inhalation time \>2.0 seconds after training, for at least three (3) times, with a maximum of 5 attempts. Exclusion Criteria: * Concurrent clinically significant cardiovascular, hematological, renal, neurologic, hepatic, endocrine, psychiatric, or malignant diseases. * Known intolerance or hypersensitivity to any component of the study drugs (i.e., Epinephrine, Albuterol Sulfate or any sympathomimetic drugs, HFA-134a, thymol, ethanol, ascorbic acid, nitric acid, and hydrochloric acid). * Upper or lower respiratory tract infection, or other systemic infection within 6 weeks prior to Screening; * Clinically significant abnormalities in the screening/baseline ECG; prolonged corrected QT interval (QTcF) on ECG: men \>450ms, women: \>470ms; single or multiple premature ventricular contractions (PVC); * Abnormal thyroid function test (if TSH is out of range, refer to T3/T4 for thyroid function assessment); * Subject has been on other investigational drug/device studies within 30 days of Screening Visit or planned participation in another investigational drug trial at any time during this trial; * Women who are pregnant or lactating or planning a pregnancy during the study period; * Subject has donated or lost \> 500 mL of blood within 3 months of Screening; * Evidence of alcohol or drug abuse or dependency within 6 months prior to screening; or * Use of any of the prohibited drugs without appropriate washout.