A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Depression

ProgenaBiome

Overview

This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records

The goal of this Research Study is to better understand how the genetic information in subject's microbiome correlates to depression.

Study Type

OBSERVATIONAL

Conditions

Depression Clinical Depression Depression, Anxiety Depression, Postpartum Depression, Endogenous Depression in Remission Depression Chronic Depression Moderate Depression Severe

Interventions

No InterventionOTHER

There is no intervention for this study

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: 1. Signed informed consent, demonstrating that the patient understands the procedures required for the study and the purpose of the study a. May be signed by parent or legal guardian in the case of minor or adult unable to provide consent 2. Male or female of all ages. (interest is given to children who present with autism or Crohn's and whose parents wish to analyze their children's gut flora. Also of interest analysis of development of the child's microbiome. In the case of autism, the younger the child, the better to correct the neurological problems if an association is found between autism and the microbiome) 3. Diagnosis of depression based on DSM-V criteria Exclusion Criteria: 1. Refusal to sign informed consent form 2. History of bariatric surgery, total colectomy with ileorectal anastomosis or proctocolectomy. 3. Postoperative stoma, ostomy, or ileoanal pouch 4. Participation in any experimental drug protocol within the past 12 weeks 5. Treatment with total parenteral nutrition

Locations (1)

ProgenaBiome

Ventura, California, United States

Outcomes

Primary Outcomes

Correlation of Microbiome to Disease via Relative Abundance Found in Microbiome Sequencing

Relative abundance of bacterial classes within taxonomic phyla and, more broadly, within their domain will be analyzed by sequencing the gut microbiome. These data will then be categorized with

Time frame: Three years

Data from ClinicalTrials.gov

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