Video-assisted thoracoscopic surgery (VATS) has been widely used for non-small cell lung cancer (NSCLC) for nearly two decades. Usually, it was applied through three ports with at least one drainage after surgery, which often lead to acute chest pain. Therefore, fewer, smaller ports, and wider intercostal space for surgery has been required. Uniport VATS became a feasible option with the development of surgical techniques and instruments, with potentially less postoperative pain and shorter hospital stays. However, there may be some complications, or with a longer time of operation, even more difficult in lymph nodes resection during learning curve. In our study, a Randomized Controlled Trial was designed to study the operation time, perioperative blood loss, conversion rate, duration of postoperative drainage, length of hospital stay, visual analogue score of postoperative pain, complications, and survival.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
300
video-assisted thoracoscopic surgery for NSCLC using single port or two ports or three ports
video-assisted thoracoscopic surgery for NSCLC using two ports
video-assisted thoracoscopic surgery for NSCLC using three ports
The Second Hospital of Shandong University
Jinan, Shandong, China
RECRUITINGoperative time
operative time in minutes
Time frame: 1 day
perioperative blood loss
perioperative blood loss in milliliter
Time frame: 1 day
conversion rate
conversion rate in proportion
Time frame: 1 day
duration of postoperative drainage
duration of postoperative drainage in days
Time frame: within 5-7 days
length of hospital stay
length of hospital stay in days
Time frame: within 5-7 days
visual analogue score of postoperative pain
score
Time frame: within 5-7 days
complications
complications in rate
Time frame: up to 3 months
overall survival
overall survival in rate
Time frame: up to 5 years
progression- free survival
progression- free survival in rate
Time frame: up to 5 years
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