This study aims to collect clinical, radiological, pathological, molecular and genetic data including detailed clinical parameters, MR and histopathology images, molecular pathology and genetic data. This study seeks to find the prognostic and clinical significance based on molecular and genetic biomarkers/subgroups of gliomas.
Precise classification based on molecular and genetic biomarkers/subgroups for gliomas is challenging. This study aims to collect clinical, radiological, pathological, molecular and genetic data including detailed clinical parameters, MR and histopathology images, molecular pathology (1p/19q co-deletion, MGMT methylation, IDH and TERTp mutations, etc) and genetic data (Whole exome sequencing, RNA sequencing, proteomics, etc). This study seeks to find the prognostic and clinical significance based on molecular and genetic biomarkers/subgroups of gliomas.
Study Type
OBSERVATIONAL
Enrollment
3,000
Patients with newly diagnosed glioma that receive tumor resection
Department of Neurosurgery, First Affiliated Hospital of Zhengzhou University
Zhengzhou, Henan, China
RECRUITINGOverall Survival (OS)
The length of time from enrollment until the time of death (OS, overall survival)
Time frame: From enrollment to death of patients. Estimated about 5 years.
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