Preoperative Skin Preparation Study to Evaluate the Antimicrobial Capabilities of Four Test Substances

Inclusion Criteria: 1. Male or female at least 18 years of age and of any race 2. In good general health 3. Read, understand and sign the Informed Consent Form (ICF) 4. If female of child-bearing potential, are willing to use an acceptable method of contraception to prevent pregnancy (i.e. oral contraceptive, intra-uterine device, diaphragm, condom, abstinence, bilateral tubal ligation, or are in a monogamous relationship with a partner who has had a vasectomy) 5. Female subjects of child-bearing potential, must have a negative Urine Pregnancy Test (UPT) on Treatment Day prior to any applications of the study products Exclusion Criteria: 1. Exposure of test sites to antimicrobial agents, medicated soaps, medicated shampoos, or medicated lotions, use of biocide-treated pools or hot tubs, use of tanning beds, or sunbathing during the 14-day washout conditioning period and during the test period 2. Exposure of the test sites to strong detergents, solvents, or other irritants during the 14-day washout conditioning period and during the test period 3. Wear fabric softener, bug repellent or UV-treated clothing during the 14-day washout conditioning period and during the test period 4. Receive an irritation score of 1 (any redness, swelling, rash, or dryness present at any treatment area) for any individual skin condition prior to the Treatment Day baseline sample collection 5. Use of systemic or topical antibiotic medications, steroid medications (other than for hormonal contraception or post-menopausal reasons), or any other product known to affect the normal microbial flora of the skin during the 14-day washout conditioning period and during the test period 6. Known allergies or sensitivities to vinyl, latex (rubber), alcohols, metals, inks, or tape adhesives, or to common antibacterial agents found in soaps, lotions, or ointments, particularly isopropyl alcohol or chlorhexidine gluconate 7. A medical diagnosis of a physical condition, such as a current or recent severe illness, asthma, diabetes, hepatitis, an organ transplant, mitral valve prolapses, congenital heart disease, internal prostheses, or any immunocompromised conditions such as AIDS (or HIV positive) 8. Pregnancy, plans to become pregnant within the washout and test periods of the study, or nursing a child 9. Any tattoos or scars within 2" (5.08 cm) of the test sites 10. Dermatoses, cuts, lesions, active skin rashes, or breaks or other skin disorders within 6" on or around the test sites 11. A currently active skin disease or inflammatory skin condition (for example, contact dermatitis) anywhere on the body that, in the opinion of the Consulting Physician or PI, would compromise subject safety or study integrity 12. Showering, bathing, or swimming within the 72-hour period prior to sampling for Treatment Day, and throughout the test period 13. Participation in another clinical study in the past 30 days or current participation in another clinical study at time of signing informed consent 14. Any medical condition or use of any medications that, in the opinion of the PI, should preclude participation 15. Unwillingness to fulfill the performance requirements of the study.