A combination of correct interpretation of imaging and biopsy has given promising results in terms of detecting clinically significant cancer at radical prostatectomy.
Quantitative approaches to medical image analysis have been developed in recent years with the aim to overcome the limitation of qualitative image interpretation, and provide biomarkers for disease characterization. In particular, the new paradigm, "radiomics", is emerging as the high-throughput extraction of quantitative features from imaging which can aid in characterizing phenotype as in vivo expression of tumoral genotype. The goal of radiomics is to extract accurate and reliable quantitative biomarkers which enhance diagnostic confidence in oncology. A combination of correct interpretation of imaging and biopsy has given promising results in terms of detecting clinically significant cancer at radical prostatectomy.
Study Type
OBSERVATIONAL
Enrollment
200
IRCCS Ospedale San Raffaele
Milan, Italy
Number of surrogate bioimaging markers of histological characteristics in MR images
Segment tumor volumes on the ADC map and extract different imaging features
Time frame: 0-2 years
Radiomic features from MRI
Evaluate if radiomic features on primitive prostate lesions can describe lymph node involvement.
Time frame: 0-2 years
Extract radiomic features
Evaluate if radiomic features fro MRIon primitive prostate lesions can describe disease extension.
Time frame: 0-2 years
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