cfDNA in Diagnosis and Differential Diagnosis of Ovarian Endometriosis

1\. Marker selection group: 1. patients with ovarian endometriosis: Inclusion Criteria: 1. pathologically diagnosed as ovarian endometriosis; 2. surgery was performed in PUMCH Exclusion Criteria: a. combined with other gynecological benign and malignant tumors; b. clinically suspected malignant tumors; c. combined with other systemic malignancies or malignancies history; d. pregnant patients 2. patients with ovarian cancer: Inclusion Criteria: 1. pathologically diagnosed as epithelial ovarian cancer; 2. surgery was performed in PUMCH Exclusion Criteria: 1. combined with gynecological benign tumors and other malignant tumors; 2. combined with other systemic malignancies or malignancies history; 3. pregnant patients (3) patients with other benign ovarian tumors: Inclusion Criteria: 1. pathologically diagnosed as benign ovarian tumors but not ovarian endometriosis; 2. surgery was performed in PUMCH Exclusion Criteria: a. combined with other gynecological benign and malignant tumors; b. clinically suspected malignant tumors; c. combined with other systemic malignancies or malignancies history; d. pregnant patients 2\. Marker validation group: Inclusion Criteria: 1. ovarian cysts found through ultrasound ; 2. surgery will be performed in PUMCH Exclusion Criteria: 1. combined with other gynecological benign and malignant tumors; 2. clinically suspected malignant tumors; 3. combined with other systemic malignancies or malignancies history; 4. pregnant patients