Investigation of Potential Retinal Toxicity Associated With Hair Dye Products Containing pPD Type Aromatic Amines

Fondation Ophtalmologique Adolphe de Rothschild62 enrolled

Overview

Hair dye products could induce minimal forms of MEKAR retinopathies (Mitogen-activated Extracellular signal-regulated Kinase - inhibitors associated retinopathies). These minimal forms of MEKAR are likely to be underdiagnosed, since the associated visual loss is usually mild and so this condition should be considered when patients report blurred vision. The aim of the study is to analyze whether in the current population that dyes the hair, minimal forms that go unnoticed by MEKAR retinopathies can be induced.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

MEK Inhibitor-Associated Serous Retinopathy

Interventions

OCT-B scan

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Hair dye up to one month before the inclusion * Hair dye product containing aromatic amines Exclusion Criteria: * Pregnant or lactating woman * Retinal pathology already known, or central serous choroiditis

Outcomes

Primary Outcomes

% of patients with MEKAR retinopathy detected on OCT-B scan

Physiological parameter : Serous retinal detachment at the posterior pole, detected on OCT-B scan

Time frame: Day of inclusion, up to one month month after the last hair dye