Feasibility and Comparison of the Impact of different Frailty Assessment Tools on the Outcome of Ventricular Assist Device Implantation and Heart Transplantation in advanced heart failure patients
Comparison of the feasibility and results of the following frailty assessment tools in advanced heart failure patients treated with ventricular assist device Implantation or awaiting heart transplantation in Eurotransplant-Status "high urgency": * Evaluation of the muscle mass in the preoperative CT-Scan * Bioelectrical Impedance Analysis * 6 Minute Walk Test * Grip Strength Measurement * Questionnaires: EQ5D-5L, Rockwood Frailty Scale The assessment will be conducted prior to surgery, after surgery and at 6 Month Follow-up
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
150
Bioelectrical Impedance Analysis 6 Minute Walk Test Grip Strength Questionnaires Muscle Mass Evaluation via CT
German Heart Center
Berlin, Germany
RECRUITINGIncidence of not performed tests due to clinical concerns/inability of the patient (feasibility and safety)
Number of patients, who were not able to perform tests and reasons
Time frame: Pre-operative measurements,
Incidence of not performed tests due to clinical concerns/inability of the patient (feasibility and safety)
Number of patients, who were not able to perform tests and reasons
Time frame: post-operative measurements in the week before discharge (average 4 weeks)
Incidence of not performed tests due to clinical concerns/inability of the patient (feasibility and safety)
Number of patients, who were not able to perform tests and reasons
Time frame: 6 Month Follow-up
Impact of frailty estimated by the different frailty assessment tools on the outcome 6 month mortality and/or prolonged ventilation time
Combined Endpoint: Endpoint is met if the Patient dies within 6 month after surgery and/or needed of a prolonged ventilation time of \>95h during the ICU stay after surgery
Time frame: After 6 Month
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