Ultrasonographic and MRI Explorations of Infraspinatus Muscle in Postero-superior Rotator Cuff Tear

University Hospital, Tours3 enrolled

Overview

The project aims to evaluate the contribution of texture analysis on MRI sections, and the technical feasibility, reproducibility, and clinical relevance of quantitative ultrasound and elastography to characterize the composition and volume of infraspinatus muscle in postero-superior rotator cuff tears. The perspectives are to optimize the imaging to allow a quantitative, objective and reproducible analysis of the muscle tissue and its characteristics.

The rotator cuff of the shoulder consists of 4 tendinomuscular units including the infraspinatus. This complex system fulfils a double role: stabilization/coaptation (raising the arm) and arm mobility (especially external rotation). Rupture of rotator cuff tendons is frequent (\> 80% among chronic shoulder pain). They go with a decrease in muscle volume (amyotrophy) and irreversible fat infiltration. The treatment is medical and then surgical (if necessary). The degrees of atrophy and muscle infiltration (especially infraspinatus) are the criteria of choice for surgery. Actually, they are assessed in MRI according to the classification of Fuchs; it is operator dependent, qualitative and poorly reproducible with a strong inter-observer variability. Our team highlighted (2016) the possibility of using texture analysis software to objectively measure the proportion of fatty tissue on MRI sections of the cuff rotator muscles. This work also showed the possibility of using mode B ultrasound for morphological imaging and shear wave elastography to estimate the elasticity of the infraspinatus. The project aims to evaluate the contribution of texture analysis on MRI sections, and the technical feasibility, reproducibility, and clinical relevance of quantitative ultrasound and elastography to characterize the composition and volume of infraspinatus muscle in postero-superior rotator cuff tears. The perspectives are to optimize the imaging to allow a quantitative, objective and reproducible analysis of the muscle tissue and its characteristics.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Rotator Cuff Tears

Interventions

MRIOTHER

MRI on both shoulder

ultrasonographic explorationsOTHER

ultrasound and elastography explorations on both shoulder

Eligibility

Sex: ALLMin age: 35 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ≥ 35 years-old and ≤75 years-old * tendonous, transfixing, postero-superior, unilateral and symptomatic rotator cuff lesions * controlateral shoulder without symptom, without rotator cuff injuries, without medical ou surgical history * written informed consent * affiliation to a social security system Exclusion Criteria: * pregnant woman * patient under legal protection * contraindications to MRI * traumatic or surgical or medical relevant history on shoulder * general or local disease affecting the skeletal striated muscle

Locations (1)

Chu Tours

Tours, France

Outcomes

Primary Outcomes

MRI Texture Index (MTI)

MRI texture index (MTI) on the healthy side and pathological side

Time frame: up to 2 months

Secondary Outcomes

Ultrasound Texture Index (UTI)

Ultrasound Texture Index (UTI) on the healthy side and pathological side

Time frame: up to 2 months

velocity of shear wave in m.s-1

shear wave velocity on the healthy side and pathological side

Time frame: up to 2 months

Data from ClinicalTrials.gov

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