Reverse Trendelenburg position has been shown to slightly reduce the intracranial pressure associated with pneumoperitoneum. However, there are no studies on the effect of the timing of reverse Trendelenburg position on intracranial pressure. This study will monitor the effect of reverse Trendelenburg position before or after pneumoperitoneum on intracranial pressure and regional cerebral oxygen saturation.
The literature includes studies that investigate the relationship of pneumoperitoneum and different positions with intracranial pressure during laparoscopy. Reverse Trendelenburg position has been shown to slightly reduce the intracranial pressure associated with pneumoperitoneum. However, there are no studies on the effect of the timing of reverse Trendelenburg position on intracranial pressure. This study will monitor the effect of reverse Trendelenburg position before or after pneumoperitoneum on intracranial pressure and regional cerebral oxygen saturation. Ultrasound guided measurement of the optic nerve sheath diameter as a non-invasive method will be used for measurement. The investigators believe reverse Trendelenburg position before pneumoperitoneum may prevent undesired sudden increases in intracranial pressure.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
79
Before Reverse Trendelenburg Position
After Reverse Trendelenburg Position
Bagcilar Training and Research Hospital
Istanbul, Turkey (Türkiye)
Change in Optic Nerve Sheath Diameter
The change in intracranial pressure via optic nerve sheath diameter measurement during laparoscopic cholecystectomy among 6 time point.
Time frame: Throughout the surgery
Change in regional cerebral oxygen saturation
The change in regional cerebral oxygen saturation during laparoscopic cholecystectomy among 6 time point.
Time frame: Throughout the surgery
Perioperative Hemodynamic Parameters
Mean arterial pressure in mmHg
Time frame: Throughout the surgery
Perioperative Hemodynamic Parameters
Heart rate beat per minute
Time frame: Throughout the surgery
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