Breath Stacking Technique Associated With Expiratory Muscle Training in Amyotrophic Lateral Sclerosis Patients

Escola Superior de Ciencias da Saude50 enrolled

Overview

it will be conducted a randomized parallel controlled trial with patients diagnosed with Amyotrophic Lateral Sclerosis (ALS) to compare two techniques to lung recruitment and cough augmentation, to assess their effects on pulmonary function, global functionally, swallowing and ability to speech in these population.

age over 18 years preserved cognition, evidenced by a score greater than or equal to 24 points in the Mini-Mental Status Exam; no barium allergies; without tracheostomy or invasive mechanical ventilation; no diaphragmatic pacemaker and without associated respiratory disease.Participants are excluded if they have pregnancy; previous kidney disease or other concomitant diseases; respiratory diseases and hospitalization in intensive care units (ICUs) during the study.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Amyotrophic Lateral Sclerosis Neuromuscular Diseases

Interventions

Breath Stacking GroupDEVICE

Lung recruitment technique using manual bag resuscitation with oronasal mask interface

Breath stacking and EMTDEVICE

Lung recruitment technique with one way valve with counter resistance during all expiratory phase

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * diagnosis of neuromuscular disease confirmed by neurologists at the referral center for neuromuscular diseases at Brasília prior to screening for recruitment * age over 18 years * preserved cognition, evidenced by a score greater than or equal to 24 points in the Mini-Mental Status Exam; * no barium allergies * without tracheostomy or invasive mechanical ventilation * no diaphragmatic pacemaker * without associated respiratory disease Exclusion Criteria: * pregnancy * previous kidney disease or other concomitant diseases .respiratory diseases and hospitalization in intensive care units (ICUs) during the study.

Locations (1)

Hospital de Apoio de Brasilia

Brasília, Federal District, Brazil

Outcomes

Primary Outcomes

maximal respiratory pressures

change of decline rate of maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) assessed by digital pressure (MVD-500 V.1.1 Microhard System,Porto Alegre, Brazil).