Periodontal regeneration can change tooth prognosis and represents an alternative to extraction in teeth compromised by severe intrabony defects. The aim of this study is to compare periodontal regeneration (PR) with tooth extraction and replacement (TER) in a population with attachment loss to or beyond the apex of the root in terms of professional, patient reported and economic outcomes.
This was a single center 10-year randomized controlled clinical trial. 50 stage III or IV periodontitis subjects with a severely compromised tooth with attachment loss to or beyond the apex were randomized to PR or TER with either an implant or a tooth supported fixed partial denture. Subjects were kept on a strict periodontal supportive care regimen every 3 months and examined yearly. Survival, complication free survival, recurrence analysis, oral health related quality of life and patient reported outcomes analyses will be performed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
50
Faculty of Dentistry, The University of Hong Kong
Hong Kong, Hong Kong
Tooth or tooth replacement survival
Presence of functional and symptoms free tooth or tooth replacement
Time frame: 10 year
Occurrence and cost of management of recurrence
Recurrence analysis
Time frame: 10-year
Oral health related quality of life: OHIP-14 (Oral Health Impact Profile)
14 validated questions, 5 point Liker scale, smaller scores represent better outcome (smaller impact on quality of life)
Time frame: 10 years
Clinical attachment level gain
Control outcome of periodontal regeneration
Time frame: 10 years
Probing pocket depth
Control outcome of periodontal regeneration
Time frame: 10 years
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