Giving a Low Carbohydrate Diet to Overcome Hypertension

Baylor Research Institute64 enrolled

Overview

This study will test the preliminary efficacy of adding a very low carbohydrate dietary intervention to the evidence-based DPP-GLB on blood pressure reductions for lower-income AA men and women in a community-based clinic.

This study will evaluate the effects of consuming a very low carbohydrate (VLC) diet in a sustainable community care setting, in addition to routine medical care, to African American (AA) with pre-hypertension, hypertension (stage 1-3), or cardiovascular disease risk factors. This study will also secondarily assess the feasibility of following a VLC diet in a low-income, AA population.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Hypertension African Americans Diet, Carbohydrate-Restricted Risk Reduction Behavior

Interventions

Very low carbohydrate dietOTHER

Participants will learn to follow a very low carbohydrate diet in modified versions of GLB modules 2,3,5 \& 10. Participants will learn to track carbohydrate intake

Standard DPP-GLB dietOTHER

Participants will learn to follow a very low fat, calorie-restricted diet and track fat grams and caloric intake in standard GLB modules 2,3,5, \& 10

Standard DPP-GLB program modulesBEHAVIORAL

Participants will learn standard DPP-GLB modules for other lifestyle modifications for stress, physical activity, etc. in sessions 1,4,6-9, 11-22

Eligibility

Sex: ALLMin age: 18 YearsMax age: 74 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * 1\) men and women aged ≥ 18 years * 2\) willingness to participate in a 10-month study * 3\) systolic blood pressure \> 120 mm/Hg +/- diastolic blood pressure \> 80 mm/Hg * 4\) African American race Exclusion Criteria: * 1\) diagnosed congestive heart failure * 2\) Hypertension stage 4 or higher (e.g., SBP \>180 mm/Hg; DBP \> 110 mm/Hg) * 3\) received or needing more than 3 anti-hypertensive medications * 4\) pregnant or planning to become pregnant * 5\) receiving or needing a heart transplant * 6\) Using injected long or short-acting insulin for diabetes treatment * 7\) not African American race * 8\) unable to speak and read English with fluency

Locations (1)

Baylor Research Institute

Dallas, Texas, United States

Outcomes

Primary Outcomes

Changes in Systolic blood pressure

Measure changes in both systolic and diastolic blood pressure using digital sphygmomanometer; NOTE: Only Systolic BP is primary outcome, diastolic change will be a secondary outcome measure