NCT04233177 - The Effect of Trendelenburg Position on CCA Blood Flow | Crick | Crick

The Effect of Trendelenburg Position on CCA Blood Flow

N/ACompletedNCT04233177

Seoul National University Hospital20 enrolled

Overview

The investigators will evaluate the change of the common carotid artery blood flow according to patient's position and penumoperitoneum.

The study will include 20 patients undergoing gynecological surgery. The common carotid artery blood flow will be measured using Doppler US during the following conditions; supine position before induction of anesthesia, supine position immediately after induction of anesthesia, supine position with penumoperitoneum, head-down position with or without pneumoperitoneum.

Study Type

OBSERVATIONAL

Enrollment

20

Conditions

Perfusion Perioperative/Postoperative Complications

Eligibility

Sex: ALLMin age: 20 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * ASA class I,II * patients undergoing gynecology surgery under trendelenburg position * Age ranges from 20 to 70 Exclusion Criteria: * BMI \> 32 * Pregnancy * Patients who did not agree to study * Patients with allergies to the drugs used in this study * Patients with anatomical variations or lesions in cervical or cranial vascular portion * Patients with arrhythmia that may alter patient's cardiac output(e.g. artrial fibrillation)

Locations (1)

Jin-Tae Kim

Seoul, South Korea

Outcomes

Primary Outcomes

Change of the common carotid artery blood flow velocity

Common carotid artery blood flow velocity is measured using Doppler US

Time frame: 1) baseline, 2) Immediately after induction of anesthesia, 3) immediately after pneumoperitoneum, 4) immediately after Trendelenburg position with penumoperitoneum, 5) Immediately after desufflation in Trendelenburg position

Secondary Outcomes

Change of the common carotid artery beat volume

Common carotid artery beat volume was calculated from median common carotid artery beat velocity and vessel diameter

Time frame: 1) baseline, 2) Immediately after induction of anesthesia, 3) immediately after pneumoperitoneum, 4) immediately after Trendelenburg position with penumoperitoneum, 5) Immediately after desufflation in Trendelenburg position

Change of the common carotid artery diameter

Common carotid artery diameter is obtained using US

Time frame: 1) baseline, 2) Immediately after induction of anesthesia, 3) immediately after pneumoperitoneum, 4) immediately after Trendelenburg position with penumoperitoneum, 5) Immediately after desufflation in Trendelenburg position

Change of mean arterial blood pressure

Mean arterial pressure is obtained concurrently with common carotid artery blood flow velocity measurements

Time frame: 1) baseline, 2) Immediately after induction of anesthesia, 3) immediately after pneumoperitoneum, 4) immediately after Trendelenburg position with penumoperitoneum, 5) Immediately after desufflation in Trendelenburg position

Change of cardiac output

Cardiac output was obtained using FloTrac(EdwardLifescience, USA)

Time frame: 1) baseline, 2) Immediately after induction of anesthesia, 3) immediately after pneumoperitoneum, 4) immediately after Trendelenburg position with penumoperitoneum, 5) Immediately after desufflation in Trendelenburg position

Data from ClinicalTrials.gov

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