The objectives of this study were to evaluate efficacy and safety of silicone cream containing Allium Cepa extract in post-cesarean surgical scars treatment. Post-cesarean surgical scars were equally seperated into 2 parts (left part and right part). Silicone cream containing Allium Cepa extract or commercial scar gel was ramdomly assigned to apply on left part or right part of the scar. They will be applied 2 times per day (morning and evening) for 3 months. Patient and Observer Scar Assessment Scale (POSAS) , Vancouver scar scale (VSS), melanin index, and erythema index (using cutometer) were used for scar evaluation at 0, 1,2,and 3 months. Moreover, adverse effects were also observed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
22
silicone cream containing Allium Cepa extract contains 10% of Allium cepa bulb extract.
Commercial scar gel is a topical silicone gel. It contains cyclic and polymeric siloxanes and Vitamin C ester.
Patient and Observer Scar Assessment Scale
The range of score is 1 to 10. Noraml skin will be recorded as scale 1. Higher scores mean a worse outcome.
Time frame: 3 months
Vancouver scar scale
The range of score is 0 to 10. Higher scores mean a worse outcome.
Time frame: 3 months
Melanin index
Melanin index will be evaluated using cutometer.
Time frame: 3 months
Erythema index
Erythema index will be evaluated using cutometer.
Time frame: 3 months
Adverse effect
Adverse effect will be observed in term of erythema, edema, papules, vesicles, and bullae. The range of erythema score is 0 to 3. The range of edema score is 0 to 4. Higher scores mean a worse outcome. Papules, vesicles, and bullae will be recorded as apperance or clear.
Time frame: 3 months
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