A suture is a biomedical device that is made of natural or synthetic materials. Sutures are used to close tissue surfaces until wounds heal and regain their ability to withstand normal stresses. Although different suture materials are available for various dental procedures, clinicians commonly neglect to select sutures based on their mechanical properties and capabilities. Instead, clinicians rely on their clinical experience to determine which suture material will suffice for wound closure and healing. To our knowledge, there have been no published studies detailing the results of mechanical testing on sutures after clinical application. The aim of this study is to clinically, histologically, and mechanically assess the four common sutures used in periodontal and dental surgery, with the hopes of providing clinicians with a guide that will allow them to choose sutures based on the clinical, histological, mechanical properties that best fit the stress and strain applied to the wound.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Enrollment
200
Periodontal and periimplant flaps closed with at least one suture with Polyglycolic Acid Absorbable suture, synthetic, 4-0. (TAGUM®).
Periodontal and periimplant flaps closed with at least one suture with Chromic Gut Absorbable suture, natural, 4-0. (TAGUM®)
Periodontal and periimplant flaps closed with at least one suture with expanded Polytetrafluoroethylene Non absorbable suture, synthetic, 4-0. (TAGUM®)
Periodontal and periimplant flaps closed with at least one suture with Nylon Non absorbable sutures, synthetic, 4-0. (TAGUM®)
healing changes around each suture material
To determinate the healing changes around each suture material using the Healing Index of Landry and colleagues (1988)
Time frame: 1 week, 2 weeks 1 month and 3 months after surgery.
Tensile and mechanical properties of each suture material
Evaluation of the tensile mechanical properties of each suture material using a Chatilloin TCD200 jig attachment, and tensile load will be applied to each suture at 0.05N/mm per min. Each suture will be stretched to failure and the maximum load will be recorded in Newtons (N).
Time frame: following 1 week of clinical application.
Biofilm formation around each suture material
To determinate the biofilm formation around each suture material using PCR
Time frame: following 1 week of clinical application.
complications including erythema, edema, hematoma, infection, wound dehiscence, keloid or scar tissue
To determinate the presence of complications including erythema, edema, hematoma, infection, wound dehiscence, keloid or scar tissue
Time frame: 1 week, 2 weeks, 1 month and 3 months after surgery.
plaque adherence over sutures, number of sutures present and number of stable (untied) sutures
To determinate the plaque adherence over sutures, number of sutures present and number of stable (untied) sutures • Plaque adherence over sutures. This will be classified as following: 0: no debris or plaque present; 1. soft debris or plaque covering not more than one third of the sutures, 2. soft debris or plaque covering more than one third of the exposed suture; 3. soft debris of plaque covering more than two thirds of the exposed sutures.
Time frame: 1 week after surgery.
subject satisfaction
To determinate subject pain/satisfaction using a Visual Analogue Scale (VAS) at Visits 2 and 5. The VAS will be given to the subject in order to rate the satisfaction on a scale from 0 to 10, where 10 is the highest level of pain/satisfaction.
Time frame: 1 week and 3 months following surgery.
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