Prevention of lung inhomogeneity is an essential part of preventive strategy in neurocritical care, reducing the risks of secondary brain damage from hypoxemia, hypo/hypercapnia or pneumonia.
In the monocentric, intervention, prospective, randomized study, the investigators will examine the effect of lateral tilting (routinely used in critical care) on the lung inhomogeneity that will be analyzed by electrical impedance tomography (EIT) in the unconscious patients with acute primary brain disease and artificial pulmonary ventilation. Two types of lateral tilting will be compared: manual positioning of body by nurse versus the bed tilting (15° lateral tilt, original company (LINET) and product brand name (Eleganza 5).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
250
15° lateral tilt, original product brand name LINET Eleganza 5
Manual positioning of body by nurse: left side, back, right side, using positioning pillows
Regional Hospital Liberec
Liberec, Czechia
Atelectasis/collapse
Assessed by electrical impedance tomography (EIT) or chest x-ray (CXR) at end of observation period
Time frame: up to 24 weeks
Evaluating oxygenation parameters
Oxygen saturation
Time frame: up to 24 weeks
Evaluating hemodynamic parameters
Hemodynamic monitoring: stroke volume variation (SVV)
Time frame: up to 24 weeks
Cost effectiveness measurement between two groups
Therapeutic Intervention Scoring System (TISS)
Time frame: up to 24 weeks
Profiling pneumonia incidence
Pneumonia score
Time frame: up to 24 weeks
Comparing duration of stay in Neurocenter Neurointensive Care Unit
Days of hospitalization
Time frame: up to 24 weeks
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