Comparison of Articaine and Prilocaine for Extraction of Maxillary Teeth

Taibah University95 enrolled

Overview

Ninety-five patients, aged between 16 and 70 years old, were included in this study. Patients were divided into two groups. Group one received Articaine 4% with 1:00.000 Adrenalines. Group two received Prilocaine with 3% Felypressin (0.03 I.U. per ml). Onset time of anaesthesia was objectively evaluated by using electronic pulp testing.

85 patients in this study had successful local anaesthetic followed by extraction within the study duration time (10 minutes). However, there were six patients with failure anaesthesia (5 in prilocaine group and 1 in articaine group). By application Person's Chi-square test (x2), there were no significant differences in the number of the episodes of the anaesthetic success between articaine and prilocaine groups at time intervals (P-value = 0.5). T- test showed there have been no important variations within the mean onset time of anaesthesia for articaine and prilocaine buccal infiltrations (P-value =0.1).

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Overcoming the Failure of Anaesthesia Maxillary Teeth Dental Extraction

Interventions

Articaine 4%DRUG

Articaine 4% is dental local anaesthetic agent

Prilocain 3%DRUG

prilocaine is dental local anaesthetic agent

AdrenalinDRUG

adrenaline is a vasoconstrictor

Felypressin

Eligibility

Sex: ALLMin age: 16 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients have one or two upper teeth for extraction, subject tooth or its adjacent must be vital, healthy patient or patient with mild systemic diseases (class I or II according to American Society of Anesthesiology). Exclusion Criteria: * Patients excluded from this study if they have allergy to local anaesthetic agents or need surgical, or multiple teeth extraction.

Locations (1)

Taibah University

Madinah, Saudi Arabia

Outcomes

Primary Outcomes

Does articaine, rather than prilocaine, increase the success rate of anaesthesia for extraction of maxillary teeth

to compare the anaesthetic performances of 3% prilocaine (the safest local anaesthetic) with 4 % articaine (the local anaesthetic with fastest onset time of action) when used for maxillary teeth extraction

Time frame: 6 months

Data from ClinicalTrials.gov

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