The present study is a human, prospective, randomised controlled clinical trial will be conducted to explore and compare the clinical, radiographic and histomorphometric outcome of autogenous demineralised dentin(DDM) versus bovine derived xenograft(DBM) for socket preservation procedure.
* After local anesthesia a full thickness flap will be minimally reflected buccally and lingually around the tooth not exceeding 3mm apical to the alveolar crest. * Tooth extraction will be performed using atraumatic extraction methods using Periotome. * After extraction, the socket will be thoroughly curetted, inspected and irrigated with sterile saline solution. * The socket satisfying the inclusion and exclusion criteria will be randomly allocated to either test or control group. * Intra surgical measurements will be recorded. * Socket preservation will be performed with either Demineralized dentin matrix DDM(TEST) or bovine derived xenograft DBM (CONTROL). Bone graft will be extended to the height of intra proximal bone. * Collagen membrane will be placed over the grafted site extending approximately 3mm apical to buccal and lingual crest. * Flaps will be approximated with sutures.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
20
Autogenous dentin matrix and collagen membrane(test group) Bovine derived xenograft and collagen membrane (control group)
Krishnadevaray College of Dental Science and Hospital
Bangalore, Karnataka, India
RECRUITINGHeight of Alveolar Crest and Bucco-Lingual Ridge Width
Using Mapping Caliper and (University of North Carolina) UNC- 15 PROBE Measured in mm
Time frame: 6 Months
Alveolar Ridge Width Gain(ARWG) and Vertical Bone Height Gain(VBHG)
CBCT (Cone Beam Computer Tomography) measured in mm
Time frame: 6 MONTHS
New Bone Formation % and Residual Bone Graft
HISTOMORPHOMETRIC
Time frame: 6 MONTHS
Plaque Index
Silness and Leo index using UNC-15 PROBE with Rating Score Excellent- 0 Good- 0.1 - 0.9 Fair -1.0 - 1.9 Poor - 2.0 - 3.0
Time frame: 6months
Bleeding Index
Mombelli - Sulcus Bleeding Index using UNC-15 Probe with Rating Score 0- No bleeding 1 -Isolated bleeding spots visible 2-Blood forms a confluent red line on the margin 3- Heavy or profuse bleeding
Time frame: 6 months
Patient Reported Outcome Measures for Pain and Esthetics
( Visual Analog Scale -VAS) Rating score, None (0) Mild (1-3) Moderate (4-6) Severe (7-10)
Time frame: 6 months
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