Prognostic Impact of PMI in Stable CAD Undergoing PCI

Shanghai Zhongshan Hospital2,000 enrolled

Overview

This is a single-center, observational, prospective study. This study aims to observe the effect of periprocedural myocardial injury on cardiovascular events in patients undergoing elective percutaneous coronary intervention, and to detect the levels of serum inflammatory factors before and after intervention to predict the occurrence of periprocedural myocardial injury and its association with cardiovascular events.

Study Type

OBSERVATIONAL

Enrollment

2,000

Conditions

Periprocedural Myocardial Injury Coronary Artery Disease Percutaneous Coronary Intervention

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * underwent elective coronary stenting * patients permit informed consents Exclusion Criteria: * acute STEMI * NYHA class III-IV heart failure * moderate-to-severe valvular disease * missing post-PCI troponin results * active infection, respiratory failure * liver dysfunction (liver enzyme \>3xURL or bilirubin \>2xURL), * malignancy and systemic connective tissue disease * unable to get a informed consents

Locations (1)

180 Fenglin Road

Shanghai, Shanghai Municipality, China

RECRUITING

Outcomes

Primary Outcomes

Major cardiac events

cardiac death, target vessel revascularization, target lesion revascularization, non-fatal myocardial infarction, heart failure, angina pectoris

Time frame: 12 months after PCI

Secondary Outcomes

Serum level of inflammatory factors

Serum level of inflammatory factors including TNFα, IL-6 and so on.

Time frame: 1 day after PCI

Central Contacts

Zhangwei Chen, MD

CONTACT

+86 21 64041990 chen.zhangwei@zs-hospital.sh.cn

Danbo Lu, PhD

CONTACT

+86 21 64041990 lu.danbo@zs-hospital.sh.cn

Data from ClinicalTrials.gov

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