This is a prospective, multi-centre trial conducts at 4 ERCP centers in China designed to determine if chronic gallbladder diseases increase the incidence of Post-Endoscopic Retrograde Choledochopancreatography-Choledocholithiasis (PEC)
Endoscopic Retrograde Choledochopancreatography(ERCP) has the advantages of less injury and faster recovery for common bile duct stone patients. However, according to our retrospective study, ERCP will has a mostly 10% possibility to get an acute purulent cholecystitis which often requires emergency intervention, when patients combined with chronic gallbladder diseases, such as chronic cholecystitis, asymptomatic gallstones, and gallbladder wall thickness, the incidence of PEC will increase accordingly. The aim of this study is to observe if chronic gallbladder disease will increase the occurence of PEC and develop a high-risk PEC model.
Study Type
OBSERVATIONAL
Enrollment
1,019
Routine ERCP procedures with gallbladder in situ patient
Chinese herb medicine hospital of Longnan City
Longnan, Gansu, China
The first hospital of Tianshui
Tianshui, Gansu, China
Wuwei turmour hospital
Wuwei, Gansu, China
Number of Acute PEC(post-ERCP-cholecystitis )
When the PEC occurs, with right upper abdominal pain, White Blood Cell increasing, gallbladder wall ≥4mm or crudely, temperature might be more than 38 degree centigrade
Time frame: 1month
Number of Pancreatitis
Typical abdominal pain, with the level of serum amylase increasing at least 3 times of the normal range within 24 hours after ERCP.
Time frame: 1month
Number of Cholangitis
Temperature should be more than 38 #, right upper abdominal pain, chills or WBC≥10
Time frame: 1 month
Number of Perforation
Typical abdominal pain,abdominal muscle tension, tenderness, evidence of free gas in abdominal cavity
Time frame: 1 month
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