r-ESWT in Moderate Knee Osteoarthritis

Mustafa Kemal University110 enrolled

Overview

This study aims to compare the efficacy of r-ESWT treatment with sham-ESWT on pain, walking speed, physical function, and isokinetic muscle strength in knee osteoarthritis.

Extracorporeal shock wave therapy (ESWT) has been increasingly used to help relieve pain and to remedy musculoskeletal disorders in recent years. ESWT seems to be an effective treatment modality many different musculoskeletal conditions, including rotator cuff tendinopathies, calcifying tendinopathy of the shoulder, lateral epicondylitis, greater trochanteric pain syndrome, patellar tendinopathy, achilles tendinopathy, plantar fasciitis, and bone disorders. ESWT seems to have chondroprotective, anti-inflammatory, neovascularization, anti-apoptotic, and tissue regeneration effect on tissues which could be relevant in the treatment of OA.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

110

Conditions

Orthopedic Disorder

Interventions

ESWTDEVICE

Extracorporeal shock wave therapy

Eligibility

Sex: ALLMin age: 50 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Knee OA according to American College of Rheumatology (ACR) diagnostic criteria with Kellgren - Lawrence (K-L) grade 2 or 3. Exclusion Criteria: * Patients with secondary OA, * severe chronic illness, * poor general health status (heart failure, chronic bronchitis, etc.), * chronic inflammatory diseases, * knee replacement surgery, * prior malignancy

Locations (1)

Mustafa Kemal University

Hatay, Turkey (Türkiye)

Outcomes

Primary Outcomes

Visual Analog Scale (VAS)

The VAS is used to measure and monitor pain intensity. Scores range from the absence of pain (0) to intolerable pain (0 or 10)

Time frame: up to 12 weeks

Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)

Pain, joint stiffness, and physical functions were evaluated by the Western Ontario and McMaster Osteoarthritis Index (WOMAC). The WOMAC measures five items for pain (score range 0-20), two for stiffness (score range 0-8), and 17 for functional limitation (score range 0-68).

Time frame: up to 12 weeks

20-meter walk test

change from baseline on walking speed

Time frame: up to 12 weeks

isokinetic muscle performance

Isokinetic muscle performance was measured using a calibrated isokinetic test device named Humac®/NormTM Testing \& Rehabilitation System (Computer Sports Medicine Inc. Stoughton, MA, USA). The knee extensor/flexor muscle group isokinetic muscle strength \[peak torque (PT)\] of both groups was evaluated using a calibrated isokinetic dynamometer.

Time frame: up to 12 weeks

Data from ClinicalTrials.gov

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