Persistent Atrial Fibrillation (AF) APAC (Asia Pacific) Observational Study

Inclusion Criteria: 1. Signed informed consent 2. Documented symptomatic persistent AF, defined as continuous AF sustained \>7-days but \<1 year documented by: 1. Physician's note AND one of the following: 2. 24-hr Holter showing continuous AF within 90-days of the procedure OR 3. 2 ECGs (from any form of rhythm monitoring) showing continuous AF, taken at least 7-days apart 3. Refractory or intolerant to at least one Class I or III antiarrhythmic drug (AAD) as evidenced by recurrent symptomatic AF Note: Intolerant = unable, unwilling, or refusal to take AADs 4. ≥18 years of age 5. Able and willing to complete all pre-, post-, and follow-up testing and requirements Exclusion Criteria: 1. Continuous AF \>12 months (longstanding persistent AF) 2. Previous left atrial (LA) surgical or catheter ablation for AF 3. Any cardiac procedure within 90-days prior to initial procedure (Diagnostic procedures with no intervention are not considered a surgical or percutaneous surgical procedure) 4. Coronary artery bypass graft (CABG) surgery within 6-months (180-days) prior to initial procedure 5. Valvular cardiac surgical/percutaneous procedure (i.e. ventriculotomy, valve repair or replacement and/or presence of a prosthetic or mechanical valve) 6. Any carotid stenting or endarterectomy 7. Documented or known left atrial thrombus on imaging 8. Left atrial (LA) diameter \>50 mm (parasternal long axis view or by CT) 9. Left Ventricular Ejection Fraction (LVEF) \<40% 10. Unable to take anticoagulation medication due to contraindication or intolerance 11. History of blood clotting or bleeding abnormalities 12. Myocardial Infarction (MI), acute coronary syndrome, Percutaneous coronary intervention (PCI) within the 3-months (90-days) prior to the initial procedure 13. Documented thromboembolic event (including TIA) within 12-months (365 days) prior to the initial procedure 14. Rheumatic heart disease 15. Uncontrolled heart failure or New York Heart Association (NYHA) Class III or IV 16. Severe mitral regurgitation (regurgitant volume ≥ 60 mL/beat, regurgitant fraction ≥ 50%, and/or effective regurgitant orifice area ≥ 0.40cm2) 17. Awaiting cardiac transplantation or other cardiac surgery within 12-months (365 days) following the initial ablation procedure 18. Unstable angina at the time of the initial procedure 19. Acute illness or active systemic infection or sepsis 20. AF secondary to electrolyte imbalance, thyroid disease, acute alcohol intoxication, major surgical procedure in the preceding 3-months, or other reversible or non-cardiac cause 21. Diagnosed atrial myxoma 22. Presence of implanted implantable cardioverter defibrillator (ICD) or cardiac resynchronization therapy-defibrillator (CRT-D) 23. Significant pulmonary disease, (e.g., restrictive pulmonary disease, constrictive or chronic obstructive pulmonary disease) or any other disease or malfunction of the lungs or respiratory system that produces chronic symptoms 24. Significant congenital anomaly or other anatomic or comorbid medical problem that in the opinion of the investigator would preclude enrollment in this study or compliance with the follow-up requirements or impact the scientific soundness of the clinical trial results 25. Pregnant or nursing subjects and those who plan pregnancy during the clinical investigation follow-up period 26. Enrollment in an investigational study evaluating another device, biologic, or drug that may interfere with this clinical investigation at the time of the initial procedure or within 30 days prior to the initial procedure 27. Presence of any condition that precludes appropriate vascular access or manipulation of catheter 28. Life expectancy less than 12-months 29. Body mass index \>40 kg/m2 30. Known sensitivity to contrast media (if needed during the procedure) that cannot be controlled with pre-medication 31. Renal failure requiring dialysis 32. Presence of other medical, social, or psychological conditions that, in the investigator's opinion, could limit the subject's ability to participate in the clinical investigation or to comply with follow-up requirements, or impact the scientific soundness of the clinical investigation results 33. History of atriotomy or ventriotomy 34. Implanted left atrial appendage occlusion device