INvestigational Study Into Transplantation of the Uterus

N/AUnknownNCT04244409

Womb Transplant UK10 enrolled

Overview

Observational study on cohort of 10 women undergoing uterine transplantation using deceased donors

Study Type

OBSERVATIONAL

Enrollment

Conditions

Mayer-Rokitansky-Kuster Syndrome Asherson's Syndrome Postpartum Hemorrhage Cervical Cancer

Eligibility

Sex: FEMALEMin age: 24 YearsMax age: 38 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Female 2. Age - 24-38 (or 40 if eggs frozen \<38) 3. AUFI 1. Normal length vagina 2. No renal pathology 4. BMI \<30kg/m2 5. ASA grade I 6. Meet psychological criteria 7. Meet HFEA criteria for IVF 8. Eligible for NHS treatment 9. Speak fluent English Exclusion Criteria: 1. Unsuccessful oocyte retrieval (\<10 good quality embryos) 2. Previous multiple/significant surgeries 3. Severe endometriosis 4. Cancer patients \<5 years in remission 5. Previous living childbirth, adopted child or child born through surrogacy 6. HIV or Hepatitis B / C positive 7. Skin or intestinal neovagina

Locations (1)

Hammersmith Hospital, Imperial College NHS Trust

London, United Kingdom

RECRUITING

Outcomes

Primary Outcomes

Live birth rate

Time frame: 5 years

Secondary Outcomes

Pregnancy rate

Time frame: 5 years

Transplant success rate

Time frame: 3 years

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.