The Microcirculatory Characteristics of the Heart and Lung Meridians: A Study of CSAP Patients and Healthy Adults

Inclusion Criteria: Inclusion criteria for the CSAP group * Patients should meet the diagnostic criteria of coronary heart disease, which includes the following items: 1)confirmed old myocardial infarction (MI), or a history of percutaneous coronary intervention(PCI), or coronary artery bypass grafting; 2)50% or more luminal stenosis in at least one coronary artery or major branch segment confirmed by coronary angiogram or CT angiography; 3) myocardial ischemia indicted by exercise stress radionuclide myocardial imaging; 4) treadmill exercise testing is positive (for male patients); * Patients should meet the diagnostic criteria of CSAP and the Canadian Cardiovascular Society(CCS) classification for CSAP is level II or III; * The medical history of CSAP is more than 3 months with attacks occurring at least twice weekly in the last month; * 35 ≤ age ≤75 years, male or female; * Patients have clear consciousness and could communicate with others normally; * Patients could understand the full study protocol and written informed consent is signed. Inclusion criteria for health volunteers * Healthy volunteers should provide a recent medical examination report to confirm they have not any cardiovascular, respiratory, digestive, urinary, hematological, endocrine and neurological disease; * age≥20 years, male or female; * Participants have clear consciousness and could communicate with others normally; * Participants could understand the full study protocol and written informed consent is provided by themselves or their lineal kin. Exclusion Criteria: Exclusion criteria for the CSAP group * Patients with acute coronary syndrome and severe arrhythmias; * Patients'chest pain is caused by valvular heart disease, hypertrophic cardiomyopathy and dilated cardiomyopathy; * Patients'chest pain is caused by non-cardiac disease; * Patients have concomitant conditions of lung diseases, such as obstructive pulmonary disease; * Patients have serious concomitant conditions and fail to treat them effectively, such as diseases of the digestive, urinary, respiratory, hematological and nervous system; * Patients have mental illness, severe depression, alcohol dependence or history of drug abuse; * Pregnant or lactating patients; * Patients are participating in other trials. Exclusion criteria for health volunteers * Participants have mental illness, severe depression, alcohol dependence or history of drug abuse; * Pregnant or lactating participants ; * Participants are participating in other trials.