Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic ACL Surgery

University Hospitals Cleveland Medical Center49 enrolled

Overview

1. The investigators aim to examine the use of IV and oral ketorolac as an adjunctive agent to the standard of care pain protocol for postoperative pain control following ACL reconstruction surgery. 2. The investigators hypothesize that the use of IV and oral ketorolac in addition to the standard of care pain protocol will reduce postoperative opioid consumption following ACL reconstruction surgery.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

ACL Injury Postoperative Pain

Interventions

KetorolacDRUG

Oral ketorolac for pain control following ACL reconstruction surgery

Oxycodone-AcetaminophenDRUG

Oral oxycodone-acetaminophen for post-operative pain control

Eligibility

Sex: ALLMin age: 18 YearsMax age: 89 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients between 18 and 89 years old * Patients undergoing primary anterior cruciate ligament (ACL) reconstruction surgery Exclusion Criteria: * Patients below age 18 or above age 89 * Illiterate or non-English speaking individuals * Patients with contraindications to Ketorolac * History of chronic alcohol or drug abuse * Chronic use of psychotropic or analgesic drugs * Known peptic ulcer disease or bleeding diasthesis * Renal dysfunction (estimated glomerular filtration rate \< 50 mL/min/1.73m2) * Breastfeeding women * Pregnant women

Locations (1)

UH Cleveland Medical Center

Cleveland, Ohio, United States

Outcomes

Primary Outcomes

Postoperative Visual Analogue Scale Scores

Patients will record their pain on a visual analogue scale with a minimum score of 0 and a maximum score of 100 where lower values indicate a lower pain level, and higher values indicate a higher pain level.

Time frame: Up to 8 weeks postoperative

Secondary Outcomes

Narcotic Medication

Number of oxycodone-acetaminophen tablets

Time frame: 5 days

Data from ClinicalTrials.gov

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