The aim of the this study is to assess the short term physiological effects of 3 ventilation strategies for adult patients with ARDS admitted to intensive care unit. Two of those strategies are based on electrical impedance tomography (EIT) monitoring.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
22
Patients are ventilated in randomized order with three different ventilation strategies (A,B and C)
CHU Angers
Angers, France
Change in PaO2 (mmHg)
As it is a physiological study, all the outcomes will be analyzed with the same importance!
Time frame: Time : 0 ; 45 minutes ; 90 minutes ; 135 minutes ; 180 minutes
Change in PaCO2 (mmHg)
As it is a physiological study, all the outcomes will be analyzed with the same importance
Time frame: Time : 0 ; 45 minutes ; 90 minutes ; 135 minutes ; 180 minutes
Plateau pressure (cmH2O)
As it is a physiological study, all the outcomes will be analyzed with the same importance
Time frame: Time : 0 ; 45 minutes ; 90 minutes ; 135 minutes ; 180 minutes
Positive end expiratory pressure (cmH2O)
As it is a physiological study, all the outcomes will be analyzed with the same importance
Time frame: Time : 0 ; 45 minutes ; 90 minutes ; 135 minutes ; 180 minutes
Expiratory and inspiratory transpulmonary pressure (cmH2O)
As it is a physiological study, all the outcomes will be analyzed with the same importance
Time frame: Time : 0 ; 45 minutes ; 90 minutes ; 135 minutes ; 180 minutes
Regional ventilation distribution (%)
As it is a physiological study, all the outcomes will be analyzed with the same importance
Time frame: Time : 0 ; 45 minutes ; 90 minutes ; 135 minutes ; 180 minutes
Center of ventilation (%)
As it is a physiological study, all the outcomes will be analyzed with the same importance
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Time frame: Time : 0 ; 45 minutes ; 90 minutes ; 135 minutes ; 180 minutes
Overdistension and collapsus (%)
As it is a physiological study, all the outcomes will be analyzed with the same importance
Time frame: Time : 0 ; 45 minutes ; 90 minutes ; 135 minutes ; 180 minutes
Global and regional end expiratory lung impedance changes (IU)
As it is a physiological study, all the outcomes will be analyzed with the same importance
Time frame: Time : 0 ; 45 minutes ; 90 minutes ; 135 minutes ; 180 minutes
End expiratory lung volume (mL)
As it is a physiological study, all the outcomes will be analyzed with the same importance
Time frame: Time : 0 ; 45 minutes ; 90 minutes ; 135 minutes ; 180 minutes
Blood pressure (mmHg)
As it is a physiological study, all the outcomes will be analyzed with the same importance
Time frame: Time : 0 ; 45 minutes ; 90 minutes ; 135 minutes ; 180 minutes
Heart rate (bpm)
As it is a physiological study, all the outcomes will be analyzed with the same importance
Time frame: Time : 0 ; 45 minutes ; 90 minutes ; 135 minutes ; 180 minutes
Cardiac output (L/min)
As it is a physiological study, all the outcomes will be analyzed with the same importance
Time frame: Time : 0 ; 45 minutes ; 90 minutes ; 135 minutes ; 180 minutes