The primary purpose of this observational study was to determine if pRBC transfusions decrease the frequency of intermittent hypoxia events in very low birth weight infants (VLBW) during the first six weeks of life. The impact on non-pRBC transfusions on the frequency of intermittent hypoxia was also assessed.
Study Type
OBSERVATIONAL
Enrollment
75
pRBC and non-pRBC transfusions
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, United States
Pennsylvania Hospital
Philadelphia, Pennsylvania, United States
Temple University Hospital
Philadelphia, Pennsylvania, United States
Change in number of Intermittent hypoxia
An intermittent hypoxemia event is defined as a fall in oxygen saturations to less than 80% for \>/= 10 secs and \<3 minutes with a minimal time interval of 4 seconds between events.
Time frame: Change in number of intermittent hypoxia before (approximately 8 hours) and after transfusion (approximately 8 hours).
Hypoxia
Percent time with oxygen saturations less than 85%, 80% and 75%.
Time frame: 8 hours prior to transfusion and 8 hours after transfusion.
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