Single and Multiple Ascending Dose Study of CORT113176 in Healthy Participants

Inclusion Criteria: * Body mass index (BMI) 18.0 to 30.0 kg/m\^2, inclusive * Body weight ≤102 kg * Willing to consume a high-fat breakfast, including pork * Agrees to adhere to the contraception requirements of the protocol * Additional criteria apply. Exclusion Criteria: * Received any investigational drug or device in a clinical research study within the last 90 days * History of any drug or alcohol abuse in the last 2 years; a confirmed positive drugs of abuse test result * Regular alcohol consumption; a confirmed positive alcohol breath test at screening * Current smoker; a confirmed positive breath carbon monoxide reading; current user of e-cigarettes or nicotine replacement products in the last 6 months * Female of childbearing potential, pregnant or breastfeeding * Have a pregnant partner * Clinically significant abnormal clinical chemistry, hematology, or urinalysis result * Positive for hepatitis B surface antigen (HBsAg), hepatitis C virus antibody (HCV Ab), or human immunodeficiency virus (HIV) * Active renal or hepatic disease * History of clinically significant cardiovascular, renal, hepatic, endocrine, metabolic, respiratory, gastrointestinal, neurological, or psychiatric disorder * Any form of cancer in the last 5 years (exceptions apply) * History of adrenal insufficiency * Have a condition that could be aggravated by glucocorticoid and/or mineralocorticoid blockade * Currently using glucocorticoids or a history of systemic glucocorticoid use in the last 12 months or 3 months for inhaled products * Additional criteria apply.