VISPER: Randomised Comparison of Two OVDs in Cataract Surgery

Inclusion Criteria: 1. Patients of any gender, 50 years of age or older at the time of study enrolment 2. undergoing age-related cataract removal (phacoemulsification) and IOL implantation in one eye only 3. Patient informed of the needs and visit schedule required of the Clinical Investigational Plan and who has given his/her written informed consent 4. Planned implantation of the IOL in the capsular bag Exclusion Criteria: 1. Patients not able to / willing to give informed consent 2. Patients not able to comprehend and comply with study requirements 3. Patients scheduled for surgery to the fellow eye within 48 hrs preceding any scheduled study follow up. (Surgery date could be changed) 4. Patients not able to attend follow-up appointments for any reason 5. Patients with known hypersensitivity to anaesthetics of the amide type or hyaluronan 6. Patients with reduced corneal endothelium (e.g. Fuch's dystrophy) 7. Patients with epilepsy, impaired cardiac conduction, bradycardia, or impaired respiratory function 8. Patients being treated with tocainide for cardiac arrhythmia 9. Patients with impaired hepatic function, if the anaesthetic dose or site of application is likely to result in high blood levels 10. Mono-ophthalmic patients 11. Patients who have previously undergone cataract surgery in the contralateral eye 12. Patients with any psychosocial, or other chronic disease conditions that may affect the perception of bodily pain 13. VISTHESIA (topical and intracameral components) or ProVisc is not a suitable device for the patient for any reason 14. Patients with other pathology or condition presenting, according to the investigator opinion, a risk for the patient (to be documented in screen log) 15. Female patients who are menstruating, pregnant, breastfeeding or amenorrheic for less than 2 years at the time of surgery 16. Patients who may require the use of hyaluronidase as part of the study cataract procedure 17. Patients who may be regarded as being vulnerable (e.g. prisoners, residents of care or mental health institutions, trauma, war or disaster victims, dependent on the investigator etc.)