Choroidal Change on OCTA in Eyes With High Myopia

N/ANot Yet RecruitingNCT04255524

The First Affiliated Hospital with Nanjing Medical University200 enrolled

Overview

Myopia is a global healthy concern, especially the high myopia and pathological myopia among Asian populations. However, its mechanism still remains largely unclear. Recent findings suggested choroidal changes might be related to the development of myopia. This study is to useOCT angiography (OCT-A) to investigate parapapillary choroidal microvasculature change in myopic eyes, and try to find the cause-and-effect relationship between choroidal change and the development of myopia.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

200

Conditions

Myopia, Progressive Choroid Disease

Interventions

Optic coherence tomography angiography (OCTA)DEVICE

Using non-invasive, repeatable, mature device OCTA to obtain choroidal angio-map

Eligibility

Sex: ALLMin age: 18 YearsMax age: 55 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Spherical equivalent measurement can be included in above 4 groups 2. Willing to be followed up in the future 10 years Exclusion Criteria: 1. Deny to sign the patient consent, or deny to be followed 2. Evidence of cardiac, or diabetic, or CNS disease. 3. Clinically diagnosed with retinal or choroidal disease 4. Glucoma 5. Cataract or corneal disease that influence the quality of fundus OCTA image

Locations (1)

First Affiliated Hospital of Nanjing Medical University

Nanjing, Jiangsu, China