During laparoscopic surgery, gas infiltration and head down position cause pulmonary atelectasis. Alveolar recruitment maneuvers are beneficial in reopening collapsed alveoli and improving lung mechanics. Ventilator-driven Alveolar recruitment maneuvers may restore lung volume but it remains unknown which method is most effective. The primary aim was to compare the efficacy of two ventilator-driven ARMs method using incremental tidal volume or positive end expiratory pressure(PEEP) until plateau pressure 30 cmH20 (within driving pressure 20 cmH20).
General anesthesia promotes the formation of atelectasis, which negatively impacts respiratory function and may be associated with subsequent pulmonary complications. Especially, during laparoscopic surgery, gas infiltration and head down position cause pulmonary atelectasis. Alveolar recruitment maneuvers are beneficial in reopening collapsed alveoli and improving lung mechanics, suggesting that performing an Alveolar recruitment maneuvers after intubation, circuit disconnection, position change, intraabdominal gas infiltration. Conventional manual ARM is performed by sustained lung inflation using the reservoir bag on the anaesthesia machine with the adjustable pressure-limiting valve set to the desired inflation pressure. However, the manual ARM can lead to brief loss of positive pressure when switching back to the ventilator circuit, which results in re-collapse of alveoli. For this reason, investigators try to compare the methods of the ventilator-driven ARM.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
64
The two methods for performing an alveolar recruitment maneuver. Alveolar recruitment maneuvers consisted of a stepwise increase in tidal volume to a plateau pressure of 30 cm H2O versus a stepwise increase in PEEP H2O to a plateau pressure of 30 cm H2O.
Samsung medical center
Seoul, South Korea
the change of Atelectasis volume
electrical impedance tomography monitoring: end-expiratory lung impedance, atelectasis (%)
Time frame: intraoperative time point of intubation, pneumoperitoneum and trendelenberg position, end of surgery
the change of lung compliance value
comparison of lung compliance mL/cmH2O (static compliance=tidal volume/driving pressure) before/after recruitment maneuver
Time frame: intraoperative time point of intubation, pneumoperitoneum and trendelenberg position, end of surgery
the change of arterial blood gas analysis
comparison of PaO2/fraction of inspired oxygen (FiO2) mmHg before/after recruitment maneuver
Time frame: intraoperative time point of intubation, pneumoperitoneum and trendelenberg position, end of surgery
the change of driving pressure value
comparison of driving pressure cmH2O (plateau pressure-positive end expiratory pressure) before/after recruitment maneuver
Time frame: intraoperative time point of intubation, pneumoperitoneum and trendelenberg position, end of surgery
the change of peak pressure value
comparison peak pressure (cmH2O) before/after recruitment maneuver
Time frame: intraoperative time point of intubation, pneumoperitoneum and trendelenberg position, end of surgery
The difference of atelectasis
atelectasis score by lung ultrasonography (score range 0\~36)
Time frame: at postoperative 30 minutes
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