Brain Mechanisms of Reducing Polysubstance Use Following a Novel Body-mind Intervention

Inclusion Criteria: * (1) at least 18 years old; * (2) free of any psychiatric diagnoses or medication (besides a substance use disorder to alcohol, tobacco, or cannabis); * (3) in the past month, at least 4 episode of heavy episodic drinking; at least 3 occasion of cannabis use; and daily cigarette use for at least the past month; * (4) normal or corrected-to-normal vision; * (5) written informed consent; * (6) no previous meditation or neurofeedback (NF) experiences. Exclusion Criteria: * (1) any psychiatric diagnoses other than a substance use disorder; * (2) medical disorder(s) that may affect the central nervous system; medications that affect the central and autonomic nervous system; or a positive pregnancy test result (females); * (3) excluding cannabis, evidence of recent (past month) illicit drug use.