Obstructive Sleep Apnea Syndrome In Patients Treated For Cancer Of The Upper Aerodigestive Tract

Centre Hospitalier Sud Francilien142 enrolled

Overview

Prospective open-label, non-randomized, monocentric, cohort study, to assess the prevalence and severity of sleep apnea syndrome in patients treated for cancer of the upper aerodigestive tract. The patient follows a usual course of care including, at the end of the treatment of his cancer of the upper aerodigestive tract, screening for obstructive sleep apnea syndrome at 3 months and 6 months (Epworth score and ventilatory polygraphy)

Prospective open-label, non-randomized, monocentric, cohort study, to assess the prevalence and severity of sleep apnea syndrome in patients treated for cancer of the upper aerodigestive tract. Patients are included in the study when they are hospitalized for panendoscopy. Thereafter, it takes about 1 month to start any treatment. The duration of treatment is estimated at about 5 months (the longest regimen would be induction chemotherapy followed by surgery and adjuvant complementary treatment). After which the patient follows a usual course of care including, at the end of the treatment of his cancer of the upper aerodigestive tract, screening for obstructive sleep apnea syndrome at 3 months and 6 months (Epworth score and ventilatory polygraphy).

Study Type

OBSERVATIONAL

Enrollment

142

Conditions

Upper Aerodigestive Tract Neoplasms Obstructive Sleep Apnea-hypopnea Syndrome

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * macroscopic lesion suggestive of a cancerous tumour of the upper aerodigestive tract (oral cavity, oropharynx, larynx, hypopharynx, cavum, cervical lymph node metastases with an occult primary cancer) * awaiting anatomopathological confirmation Exclusion Criteria: * history of cancer of the upper aerodigestive tract * history of known obstructive sleep apnea syndrome * cancer of the thyroid, salivary glands, nose and paranasal sinuses * patients under guardianship or curatorship

Locations (1)

Centre Hospitalier Sud Francilien

Corbeil-Essonnes, France

Outcomes

Primary Outcomes

Occurence of obstructive sleep apnea syndrome

Obstructive sleep apnea syndrome is defined by an apnea-hypopnea index greater than or equal to 15 per hour

Time frame: 3 months after the end of treatment for cancer of the upper aerodigestive tract

Secondary Outcomes

Delay in onset of obstructive sleep apnea syndrome after completion of cancer treatment

Time frame: during the 6 months follow-up

Epworth score

The Epworth auto-questionnaire, rated from 0 (better) to 24 (worse), assess day-time sleapiness.

Time frame: at 3 months and 6 months

Occurence of obstructive sleep apnea syndrome

Obstructive sleep apnea syndrome is defined by an apnea-hypopnea index greater than or equal to 15 per hour

Time frame: 6 months after the end of treatment for cancer of the upper aerodigestive tract

Data from ClinicalTrials.gov

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