The Efficacy of Different Hormone Doses in 2019-nCoV Severe Pneumonia

Inclusion Criteria: 1.Meet the definition of severe pneumonia(Comply with any of the followings): 1. Shortness of breath,RR≥30 bpm; 2. In a resting state:SPO2≤93%; 3. PaO2/FiO2≤300mmHg. 2.2019-nCoV nucleic acid test was positive. 3.CT of the lung conformed to the manifestation of viral pneumonia. Exclusion Criteria: 1. dying state (i.e. survival time is less than 24 hours); 2. progressive malignant tumor with life expectancy less than 6 months; 3. immunosuppressive status(patients using immunosuppressants or chemotherapeutic drugs) 4. underlying diseases requiring long-term glucocorticoid treatment in the past 6 months or short-term glucocorticoid therapy in the past 4 weeks; 5. pregnancy 6. patients with glucocorticoid taboos