TruGraf® Testing in High-Risk Kidney Transplant Recipients

Inclusion Criteria: * High immune risk kidney transplant recipients defined by one of the following criteria: either a positive pretransplant donor specific anti-human leukocyte antigen (HLA) antibody, or a pre-transplant panel reactive antibody \>75%. * Recipient of a primary or subsequent deceased-donor or living donor kidney transplantation. * Stable serum creatinine (current serum creatinine \<2.3 mg/dl, \<20% increase compared to the average of the previous 3 serum creatinine levels). * Kidney transplant patients who are at least 30 days post-transplant. Exclusion Criteria: * Need for combined organ transplantation with an extra-renal organ and/or islet cell transplant. * Recipients who do not meet criteria of high-immune risk. * Recipients of previous non-renal solid organ and/or islet cell transplantation. * Infection with HIV. * Infection with BK. * Patients that have nephrotic proteinuria (urine protein \>3 gm/day).