Several studies investigating Tai Chi for hypertension have been carried out. However, investigators found the results were in high heterogeneity and poor methodological quality. Thus, investigators intend to provide high quality of the effectiveness and safety of Tai Chi for essential hypertension.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
234
Tai Chi is a traditional Chinese mind-body exercise, which combines deep-breath relaxation and gentle movements in sequence with meditation. Each session of Tai Chi will last 60 minutes, including a 10-minute warm-up, a 40-minute Tai Chi practice and a 10-minute cool-down.
Each session of walking will last 60 minutes, including a 10-minute warm-up, a 40-minute walking and a 10-minutes cool-down.
Affiliated Hospital of Chengdu University of Traditional Chinese Medicine (Sichuan Provincial Hospital of Traditional Chinese Medicine)
Chengdu, Sichuan, China
average 24-h Systolic Blood Pressure (SBP)
Time frame: change from baseline to 12 weeks after intervention
average SBP and average Diastolic Blood Pressure (DBP)
average SBP and average DBP during the daytime and night-time
Time frame: baseline, after intervention(12 week), after follow-up(24 week)
change of serum concentrations of Nitric Oxide
Time frame: baseline, after intervention(12 week)
change of serum concentrations of endothelin
Time frame: baseline, after intervention(12 week)
change of serum concentrations of thromboxane A2
Time frame: baseline, after intervention(12 week)
change of serum concentrations of vascular endothelial growth factor
Time frame: baseline, after intervention(12 week)
blood pressure measured at home with an upper arm electronic sphygmomanometer
Time frame: baseline, after intervention(12 week), after follow-up(24 week)
Medical Outcomes Study 36-Item Short Form
This scale contains eight dimensions (physical function, role physical, bodily pain, general health, vitality, social function, role emotional, mental health) and two summary components (physical and mental), with score from 0 to 100. High scores indicate a better quality of life.
Time frame: baseline, after intervention(12 week)
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