Lactoferrin Efficacy Versus Ferrous Sulfate in Treatment of Patients With Iron Deficiency Anemia

Assiut University96 enrolled

Overview

Lactoferrin (Lf) is a mammalian cationic iron binding glycoprotein belonging to the transferrin family which was discovered 70 years ago, and isolated simultaneously from human and bovine milks in 1960. It is widely distributed in all biological fluids and is also expressed by immune cells, which release it under stimulation by pathogens

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Iron Deficiency Anemia Treatment

Interventions

Lactoferrin BovineDRUG

treatment for 30 days

Ferrous SulfateDRUG

treatment for 30 days

Eligibility

Sex: ALLMin age: 2 YearsMax age: 15 Years

Medical Language ↔ Plain English

Inclusion Criteria:all patients with iron deficiency anemia from 2 to 15 years old \- Exclusion Criteria: * Anemia rather than iron deficiency anemia. * Family history of blood disease. * Patients with thalassemia trait. * Patients with chronic illness.

Locations (1)

AssuitU

Asyut, Egypt

Outcomes

Primary Outcomes

comparison of efficacy of lactoferrin versus ferrous sulfate tharapy in treatment of patients with iron deficiency anemia.

Complete blood count will be done before and after therapy to detect the effect of the therapy on serum hemoglobin(g/d)

Time frame: 30 days

Comparison of efficacy of lactoferrin versus ferrous sulfate tharapy in treatment of patients with iron deficiency anemia.

Total serum iron(ug/d) will be done before and after therapy to detect effect of the therapy on total serum iron level (ug/d)

Time frame: 30 days

Data from ClinicalTrials.gov

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