the investigators conduct a randomized, open-label trial to evaluate and compare the safety and efficacy of Xiyanping injection in patients with 2019-nCoV pneumonia.
Study Type
OBSERVATIONAL
Enrollment
426
Xiyanping injection, 10-20ml daily, Qd, the maximum daily does not exceed 500mg (20mL) + Lopinavir tablet /Ritonavir tablet or Alpha-interferon nebulization or Abidor Hydrochloride,
Lopinavir / ritonavir tablets, 2 times a day, 2 tablets at a time; alpha-interferon nebulization;Abidor Hydrochloride
Clinical recovery time
From the beginning of study drug use to fever, respiratory rate, blood oxygen saturation to normal and cough relief, and maintained for at least 72 hours or more, calculated in hours
Time frame: Up to Day 14
Complete fever time
From the beginning of research drug use to body temperature \<37.3 ℃ (underarm) or mouth temperature ≤37.5 ° C, or anal or ear temperature ≤37.8 ° C, and maintained for 24h or more
Time frame: Up to Day 14
Cough relief time
Cough score "day + night" from the beginning of study medication to cough ≤ 1 point, and maintained for 24 hours and above
Time frame: Up to Day 14
Virus negative time
From the beginning of the study drug to two consecutive times (sampling interval of at least 1 day)
Time frame: Up to Day 14
Incidence of severe or critical neocoronavirus pneumonia
Defined as the proportion of subjects exacerbated during treatment and meeting the diagnostic criteria for severe or critical neocoronavirus pneumonia
Time frame: Up to Day 14
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