Multiple Sclerosis (ME) is a degenerative, inflammatory and autoimmune demyelinating disease of the central nervous system, characterized by demyelination due to inflammation and degeneration of the myelin sheaths enveloping nerves of the eye, periventricular grey matter, brain, spinal cord and brainstem. The symptoms associated with MS include symptomatic fatigue, muscle weakness, ataxia, mobility and balance problems or cognitive problems. Strength training has been shown to improve strength and mobility in persons with MS.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
36
Ten weeks of resistance training
Testing sessions
Universidad Católica San Antonio
Murcia, Spain
Maximal Voluntary Isometric Contraction of Knee Extension
Time frame: Before the program training
Maximal Voluntary Isometric Contraction of Knee Extension
Time frame: After 10 weeks
Rate of Force Development
Time frame: Before the program training
Rate of Force Development
Time frame: After 10 weeks
Central Activation Ratio
Time frame: Before the program training
Central Activation Ratio
Time frame: After 10 weeks
Spasticity
Pendulum test
Time frame: Before the program training
Spasticity
Pendulum test
Time frame: After 10 weeks
Walking speed
Test 10 m-walks
Time frame: Before the program training
Walking speed
Test 10 m-walks
Time frame: After 10 weeks
Static balance
Romberg Test with eyes open and closed. Analysis with force plates
Time frame: Before the program training
Static balance
Romberg Test with eyes open and closed. Analysis with force plates
Time frame: After 10 weeks
Functional capacity
Sit to stand test
Time frame: Before the program training
Functional capacity
Sit to stand test
Time frame: After 10 weeks
Heart Rate Variability
Sleeping Heart Rate Variability
Time frame: Before the program training
Heart Rate Variability
Sleeping Heart Rate Variability
Time frame: After 10 weeks
Sleep Quality
Karolinska Sleep Diary and Acelerometry
Time frame: Before the program training
Sleep Quality
Karolinska Sleep Diary and Acelerometry
Time frame: After 10 weeks
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